Transgenic Murine Brain Tissue studies
Image at shows ex vivo data from i.v. administration in Tg mouse brain
PronucleanTM appears to co-localize with plaque centers but as "halo" around plaques and neurofibrillary tangles
PronucleonTM crosses the blood brain barrier
The results from this test were presented at the 2018 Alzheimers' Association International Conference in Chicago. Our abstract, A Novel Blood Test for Presymptomatic Detection of Alzheimer's Disease, can be found in the Alzheimers's & Dementia Journal, July 2018 Volume 14, Issue 7 Supplement, Page P778.